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Polycystic Kidney Disease& Kidney Cysts

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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

How to Protect Residual Renal Function for Dialysis Patients

2018-10-10 07:56

How to Protect Residual Renal Function for Dialysis PatientsAfter entering uremia, the residual renal function will be very little, but it can help remove excess water and other metabolic wastes, secrete EPO and vitamin D, and maintain the stability of internal environment as much as possible.

The residual renal function of each dialysis patient is different, and the specific value of residual renal function can be known by various test results, such as 24-hour urine volume, 24-hour creatinine or urea clearance rate, and serum cystatin C.

The easiest way is to check the total amount of urine a day.

Studies have found that an increase of 250ml of urine per day can reduce overall mortality in dialysis patients by 36 percent.

So how do we protect residual kidney function?

1. To control capacity load

Controlling the volume load can reduce the incidence of cardiovascular events.

Limiting sodium and water intake is the simplest and most effective way to reduce the capacity load of hemodialysis patients.

If repeated capacity overload, residual renal function will be lost at an accelerated rate.

In addition to the doctor's instruction, more important is the patient's self-control and the family's supervision.

2. Diuretics

Patients who still have urine after dialysis can consider using diuretics to protect residual renal function, which is especially important for peritoneal dialysis patients.

The hemodynamics of peritoneal dialysis is stable, which can protect the residual renal function. Patients with peritoneal dialysis and urine volume are recommended to take the loop diuretics (note the side effects of diuretics) routinely.

3. To apply medication to control blood pressure and protect renal function

Hypertension can lead to rapid decline of renal function, and ACEI and ARBs antihypertensive drugs can slow down the rate of decline of residual renal function.

4. To continue to treat primary disease

Active treatment of primary disease can reduce the degree of kidney damage. Even if the patient is already on dialysis, diabetes, systemic lupus erythematosus, vasculitis, etc., will continue to damage the kidney. If the treatment of primary disease is abandoned, residual renal function will be quickly lost.

In addition, avoiding the use of nephrotoxic drugs (amino glycosides, non-steroidal anti-inflammatory drugs, contrast agents, etc.), different dialysis regimens, dialysis solutions and dialysis doses all play an important role in protecting residual renal function.

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