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PKD & Kidney Cysts

Polycystic kidney disease (PKD) is a group of disorders that result from the formation and progressive enlargement of cysts in the kidneys without dysplasia, usually leading to renal failure.

Is It OK to Do Blood Transfusion with High Creatinine

2019-03-03 17:20

Is It OK to Do Blood Transfusion with High CreatinineHigh creatinine level often goes together with Kidney Failure. And kidney failure can cause various symptoms and complications, such as anemia. Is it OK to do blood transfusion with high creatinine? Go on reading to learn more information.

According to statistics, at least half of kidney patients will have anemia, and anemia will cause kidney hypoxia so as to lead to more kidney cell problems, thereby aggravating kidney disease. How to treat anemia? The first thing people think of must be iron supplementation and blood transfusion. Iron supplementation is not a big problem, but can kidney patients often transfuse blood?

Before discussing this issue, we should first know why kidney patients are prone to anemia.

In addition to filtering function, the kidney also has an important function, which is to secrete erythropoietin, or EPO for short.

The most important function of erythropoietin is to command the bone marrow to perform hematopoietic function. Therefore, if the erythropoietin secretion is insufficient, the hematopoietic activity of bone marrow will be reduced and anemia will occur, which is called "renal anemia".

In addition, kidney patients, especially those with creatinine elevation, have higher blood endotoxin levels, which lower life expectancy of red blood cells. This is also a major cause of anemia.

Then can patients with high creatinine do blood transfusion?

Blood transfusion is of no help to the production of erythropoietin, and there are toxic substances such as erythropoietin inhibitors in the blood, which can inhibit the effect of erythropoietin.

And as mentioned above, toxins in blood not only inhibit the production of new red blood cells, but also have a killing effect on existing red blood cells, which can accelerate the death of red blood cells. The decomposition of dead red blood cells can aggravate the accumulation of nitrogen metabolites, which adds an extra burden to the kidneys.

In addition, excessive blood transfusion can cause elevated blood urea nitrogen and potassium, aggravating the condition. It also increases the chances of importing hepatitis virus.

Therefore, it is not a good way to treat anemia by regular blood transfusion. Normally, as long as erythropoietin, iron, folic acid and other drugs are given in the treatment, and the appetite of patients is regulated from diet to supplement the lack of nutrients, anemia will get improved greatly.

Although it is not suitable for patients with renal failure and anemia to transfuse blood, it can not be applied mechanically in clinical practice.

Chronic renal failure patients do not need blood transfusion when hemoglobin >= 6g. If hemoglobin < 6g, and it has caused severe hypoxia in various organs, a small amount of concentrated red blood cells or a small amount of multiple transfusions can be given to patients to improve the condition of cell hypoxia.

If the patient is found to have a significant bleeding tendency, platelet suspension or fresh blood is needed.

Is it OK to do blood transfusion with high creatinine? No, it is not unless you have some special conditions. For more information on high creatinine, please leave a message below or contact online doctor.

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