PKD Clinic

Polycystic Kidney Disease& Kidney Cysts

Kidney Failure

Kidney Failure or Renal Failure is a medical condition in which the kidneys fail to adequately filter toxins and waste products from the blood. It is a slow and progressive decline of kidney function. >Kidney Failure

Kidney Failure

What is Kidney Failure?

Renal Failure or Kidney Failure is a medical condition in which the kidneys fail to adequately filter toxins and waste products from the blood. It is a slow and progressive decline of kidney function. It's usually a result of a complication from another serious medical condition. Unlike acute renal failure, which happens quickly and suddenly, chronic renal failure happens gradually - over a period of weeks, months, or years - as the kidneys slowly stop working, leading to end-stage renal disease (ESRD).

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How does PKD develop Renal Failure?

PKD is characterized by the numerous cysts growing on the kidneys. With ages growing, these cysts will enlarge, which can oppress the surrounding kidney tissues and make them hypoxic-ischemic. The hypoxic-ischemic of kidneys can result in the renal interstitial fibrosis, then Renal Failure, then finally ESRD. By age 60 about half of the people with PKD will need dialysis or kidney transplant to replace the function of their kidneys. Of children with ARPKD, about one-third will need dialysis or kidney transplant by the time they are 10 years of age.

Other common causes of Chronic Renal Failure include:

● Diabetes mellitus

● High blood pressure

● Autoimmune disorders such as systemic lupus erythematosus

● Urinary tract blockages and reflux, due to frequent infections, stones, or an anatomical abnormality that happened at birth

● Hardening of the arteries, which can damage blood vessels in the kidney

● Recurring pyelonephritis

● Excessive use of medications that are metabolized through the kidneys

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What are the symptoms of Chronic Renal Failure?

Some signs of chronic renal failure are more obvious than others. These are:

● Increased urination, especially at night

● Decreased urination

● Urine that is cloudy or tea-coloured

● Blood in the urine (not a common symptom of Chronic Renal Failure)

When the kidneys are no longer able to remove waste from the blood, toxins build up causing symptoms such as:

● Not feeling well

● Lack of energy

● Nausea

● Vomiting

● Weight loss

● Difficulty concentrating

● Difficulty breathing

● Depression

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What are the complications of Chronic Renal Failure?

Being diagnosed with chronic renal failure can be very frightening. The future of the condition, however, depends on the medical problem that caused the kidney failure, how much kidney damage has occurred, and what, if any, complications are present. Some of these complications may include:

● Anemia

● Increased risk of bleeding

● Increased risk of infection

● High blood pressure

● Dehydration

● Electrolyte abnormalities

● Fluid overload

● Mineral abnormalities

● Malnutrition

● Brittle bones

● Seizures

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What are treatment options for Chronic Renal Failure?


Generally speaking, when condition develops Chronic Renal Failure, dialysis will be commonly recommended. Dialysis is used to replace a kind of function of kidney, helping patients remove the wastes and excessive water out of body. We have to say that dialysis can maintain their lives to some extent.

However, dialysis can not replace other functions of kidneys and repair the kidney damage, so after a long term of taking dialysis, the kidney damage will become more severe and more kidney function will be lost. Moreover, some dialysis patients may suffer from the complications of dialysis, such as low blood pressure, headache, fatigue, sleepy, muscle cramps, nausea and vomiting and so on, which influences their life badly and discounts the quality of life. Now more and more patients decide to stop dialysis.

Kidney transplant

Kidney transplant is an efficient treatment, and regarded as the last hope by patients with Chronic Renal Failure in many countries. Compared to dialysis, kidney transplant can help patients live for a longer life. But waiting for a kidney donor takes years, and there are so many patients die during the wait. Moreover, it does not mean everything will be smooth after receiving kidney transplant. There are many cases find the creatinine level become higher again after a period of time. Cases like PKD, FSGS have a relatively high reoccurrence rate.


This treatment is mainly used in China. We do believe Immunotherapy is the most efficient treatment for Chronic Renal Failure, because it can treat the disease from the root. It combines western medicines, Chinese herbal medicines and advanced blood purification techniques. Here we will introduce it briefly. The various wastes and toxins and immune complexes in the blood can be eliminate by the blood purification techniques such as dialysis, plasma exchange, hemofiltration, immune adsorption, blood perfusion and so on; the western medicines will also be used in Immunotherapy to relieve the symptoms and slow the development of the diseases; while Chinese herbal medicines can eliminate those immune complexes depositing on kidneys, promote blood circulation, remove blood stasis, anti-inflammation, anti-coagulation and provide nutrition for damaged kidneys, the purpose of Chinese herbal medicines is to repair the kidney damage and enhance kidney function. As long as the kidney function can be enhanced, dialysis may be avoided or gotten rid of. Immunotherapy tells Chronic Renal Failure patients that urine stands for hopes, as long as they still have some certain urine, kidney transplant may not be the last choice. Immunotherapy includes six steps, it is a systemic and comprehensive therapy. And all the Chinese herbal medicines come from the nature, so patients don't need to worry about the side effects.

As to the Chronic Renal Failure caused by PKD, we should also shrink these cysts safely and efficiently, otherwise the kidney function will still decline. Chinese herbal medicines can shrink these cysts through increasing the permeability of cysts wall, decreasing the activity of lining cells and changing the inner and outer pressure difference of cysts wall. So the cysts fluid can be reabsorbed and then finally removed out of body with urine. The whole process will not cause any harm to kidneys.

We hope Chronic Renal Failure patients around the world could learn more about the Chinese herbal medicines. Remember that we will always be here providing you the free help.

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